Across TCGA patient cohorts, KRT3 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,680 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT3-associated proteins across cancer lineages are KRT75, KRT19, and JUP. Each is linked with KRT3 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT3-to-partner and partner-to-KRT3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT3→partner) and Y-score (partner→KRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KRT75 →	+2.415	+1.014	<.001	<.001	3	4
BRCA	KRT19 →	+1.409	+1.279	<.001	<.001	3	3
HNSC	JUP →	+0.596	+0.603	<.001	<.001	3	3
HNSC	FAM83G_S650 →	+0.875	+0.911	<.001	<.001	3	3
BRCA	KRT18 →	+1.436	+1.239	<.001	<.001	3	2
BRCA	KRT19_S35 →	+2.266	+1.475	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,680 associations by consensus.

Exploration

KRT3 survival (RNA) · tumor vs normal (RNA) · all KRT3 data types