KRT28

Across TCGA patient cohorts, KRT28 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,955 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRT28-associated GO terms across cancer lineages are Protein K11-linked ubiquitination, 'de novo' protein folding, and Positive regulation of epithelial cell differentiation. Each is linked with KRT28 in more than 6 cancer types. Because this analysis shows association rather than direction, both KRT28-to-partner and partner-to-KRT28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein K11-linked ubiquitination grouped by KRT28-low versus KRT28-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT28→partner) and Y-score (partner→KRT28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein K11-linked ubiquitination →	+0.085	+0.208	<.001	<.001	3	6
STAD	'de novo' protein folding →	+0.073	+0.152	<.001	.001	2	6
STAD	Positive regulation of epithelial cell differentiation →	+0.050	+0.178	<.001	<.001	3	5
STAD	Macromolecule depalmitoylation →	+0.077	+0.139	<.001	<.001	3	5
KIRP	Regulation of generation of precursor metabolites and energy →	+0.017	+0.023	<.001	<.001	3	5
KIRP	Cell fate determination →	+0.026	+0.014	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,955 associations by consensus.

Protein K11-linked ubiquitination by KRT28 expression — STAD

Explore this box plot interactively →