KRT28

Across TCGA pan-cancer cohorts, KRT28 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of KRT28’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where KRT28 RNA is repressed in tumor relative to normal tissue. In most cancer types KRT28 is over-expressed in tumor, although a few such as COAD and LUSC show the opposite, repressed pattern.

COAD, UCEC, and LUSC are the cancer types where KRT28 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT28 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.008	.019	4	view →
UCEC	All	All	+0.804	.024	2	view →
LUSC	Male	II,III,IV	−0.020	.034	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

KRT28–COAD

Open the COAD breakdown →