KRT27

Across TCGA patient cohorts, KRT27 protein abundance is significantly associated with the RNA expression of many other genes, with 547 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KRT27-associated genes across cancer lineages are GARS1, ACTR3, and NT5C3A. Each is linked with KRT27 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT27-to-partner and partner-to-KRT27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT27 versus GARS1 in UCEC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT27→partner) and Y-score (partner→KRT27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GARS1 →	+0.718	+2.120	<.001	.009	3	1
UCEC	ACTR3 →	+0.672	+2.343	.001	.003	3	1
UCEC	NT5C3A →	+0.520	+1.121	.008	.005	3	1
UCEC	TEKT3 →	-1.781	-1.655	<.001	.003	3	1
UCEC	FAM104A →	+0.477	+1.991	.009	.006	3	1
UCEC	IGF2BP3 →	+3.003	+1.388	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 547 associations by consensus.

KRT27 vs GARS1 — UCEC

Explore this scatter interactively →