KRT27

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KRT27 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,405 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KRT27-associated GO terms across cancer lineages are Neural crest formation, Angiogenesis, and Growth plate cartilage chondrocyte proliferation. Each is linked with KRT27 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT27-to-partner and partner-to-KRT27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neural crest formation grouped by KRT27-low versus KRT27-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT27→partner) and Y-score (partner→KRT27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONENeural crest formation →+0.141+0.518<.001.00633
BONEAngiogenesis →-0.092-0.508<.001.00733
SKINGrowth plate cartilage chondrocyte proliferation →-0.134-0.880<.001<.00133
SKINChylomicron remnant clearance →+0.859+0.972.001.00133
SKINCellular respiration →+0.062+0.788<.001.00424
SKINNucleobase catabolic process →-1.269-0.986<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,405 associations by consensus.

Neural crest formation by KRT27 expression — BONE

Box plot of Neural crest formation in KRT27-low vs KRT27-high samples in BONE.

Explore this box plot interactively →

Exploration