KRT27

Across TCGA cell cohorts, KRT27 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRT27-associated genes across cancer lineages are KCNK18, LCE1F, and C1QTNF7. Each is linked with KRT27 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT27-to-partner and partner-to-KRT27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNK18 grouped by KRT27-low versus KRT27-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT27→partner) and Y-score (partner→KRT27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	KCNK18 →	+0.020	+4.906	<.001	.006	3	1
OESOPHAGUS	LCE1F →	+0.330	+4.906	<.001	.006	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.130	+4.108	<.001	.008	3	1
LARGE_INTESTINE	OR6Q1 →	+0.015	+4.022	<.001	.006	3	1
CNS	KRTAP5-10 →	+0.022	+3.201	.003	.008	3	1
SKIN	OR5B3 →	+0.044	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

KCNK18 by KRT27 expression — OESOPHAGUS

Explore this box plot interactively →