Across TCGA patient cohorts, KRT25 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,789 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRT25-associated GO terms across cancer lineages are Regulation of protein serine/threonine kinase activity, RNA 5'-end processing, and RNA capping. Each is linked with KRT25 in more than 8 cancer types. Because this analysis shows association rather than direction, both KRT25-to-partner and partner-to-KRT25 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT25→partner) and Y-score (partner→KRT25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein serine/threonine kinase activity →	+0.053	+0.175	<.001	<.001	3	9
STAD	RNA 5'-end processing →	+0.052	+0.174	<.001	<.001	3	8
STAD	RNA capping →	+0.061	+0.176	<.001	<.001	3	8
STAD	tRNA 5'-leader removal →	+0.045	+0.178	<.001	<.001	3	8
STAD	Leukocyte apoptotic process →	+0.053	+0.165	<.001	<.001	3	7
STAD	Negative regulation of post-translational protein modification →	+0.063	+0.191	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,789 associations by consensus.

Exploration

KRT25 survival (RNA) · tumor vs normal (RNA) · all KRT25 data types