KRT25

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KRT25 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,532 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KRT25-associated GO terms across cancer lineages are Negative regulation of glycoprotein biosynthetic process, Malate transport, and Negative regulation of ERBB signaling pathway. Each is linked with KRT25 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT25-to-partner and partner-to-KRT25 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT25→partner) and Y-score (partner→KRT25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONENegative regulation of glycoprotein biosynthetic process →+0.098+0.861.008.00732
BONEMalate transport →+0.206+1.056<.001<.00132
BONENegative regulation of ERBB signaling pathway →-0.103-0.852<.001<.00132
BONEProtein localization to early endosome →-0.270-0.923<.001.00232
BONENegative regulation of vascular associated smooth muscle contraction →+0.134+0.750<.001.00132
BONERegulation of NMDA receptor activity →+1.244+0.715<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,532 associations by consensus.

Exploration