KRT24

Across TCGA patient cohorts, KRT24 mutation is significantly associated with the RNA expression of many other genes, with 2,501 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT24-associated genes across cancer lineages are RPS6P20, FOXO1B, and FARSBP1. Each is linked with KRT24 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT24-to-partner and partner-to-KRT24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS6P20 grouped by KRT24-low versus KRT24-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT24→partner) and Y-score (partner→KRT24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPS6P20 →	+0.327	+3.937	<.001	.007	3	3
LUAD	FOXO1B →	+0.208	+3.754	<.001	.008	3	2
UCEC	FARSBP1 →	+0.061	+2.060	<.001	.002	3	2
STAD	PRR23D1 →	+0.017	+3.880	.003	.003	3	2
UCEC	SRRD →	+0.447	+3.947	.001	<.001	3	2
UCEC	NDRG3 →	+0.355	+2.247	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,501 associations by consensus.

RPS6P20 by KRT24 expression — COAD

Explore this box plot interactively →