KRT24

Across TCGA pan-cancer cohorts, KRT24 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of KRT24’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where KRT24 RNA is repressed in tumor relative to normal tissue. In most cancer types KRT24 is over-expressed in tumor, although a few such as KIRC and COAD show the opposite, repressed pattern.

KIRC, COAD, and BLCA are the cancer types where KRT24 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT24 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.247	<.001	12	view →
COAD	Male	All	−2.595	<.001	11	view →
BLCA	All	All	−1.490	<.001	9	view →
KICH	Female	All	−0.428	<.001	9	view →
READ	Female	All	−2.984	<.001	7	view →
HNSC	All	II,III,IV	−2.069	.005	6	view →
STAD	Male	II,III,IV	−1.620	.002	4	view →
LUAD	All	II,III,IV	−0.109	.001	4	view →
LUSC	All	All	+0.659	.004	3	view →
THCA	Female	All	−0.048	.007	3	view →
PRAD	All	All	−0.729	<.001	2	view →
CHOL	Female	All	+0.083	.002	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

KRT24–KIRC

Open the KIRC breakdown →