KRT23

Across TCGA cell cohorts, KRT23 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,771 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT23-associated GO terms across cancer lineages are Negative regulation of hippocampal neuron apoptotic process, Maintenance of unfolded protein, and Positive regulation of epidermis development. Each is linked with KRT23 in more than 7 cancer types. Because this analysis shows association rather than direction, both KRT23-to-partner and partner-to-KRT23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hippocampal neuron apoptotic process grouped by KRT23-low versus KRT23-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT23→partner) and Y-score (partner→KRT23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of hippocampal neuron apoptotic process →	+1.175	+2.240	<.001	<.001	3	8
BREAST	Maintenance of unfolded protein →	+0.119	+2.521	<.001	.006	3	7
PANCREAS	Positive regulation of epidermis development →	+0.085	+2.517	.005	.004	3	7
URINARY_TRACT	Cellular response to indole-3-methanol →	+0.213	+2.381	<.001	<.001	3	7
OVARY	Action potential propagation →	-0.710	-2.337	<.001	<.001	3	7
URINARY_TRACT	Regulation of ruffle assembly →	+0.127	+2.389	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,771 associations by consensus.

Negative regulation of hippocampal neuron apoptotic process by KRT23 expression — URINARY_TRACT

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