Across TCGA patient cohorts, KRT222 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,348 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KRT222-associated proteins across cancer lineages are MAP1A, AKAP12_T1760, and HK2. Each is linked with KRT222 in more than 4 cancer types. Because this analysis shows association rather than direction, both KRT222-to-partner and partner-to-KRT222 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT222→partner) and Y-score (partner→KRT222) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MAP1A →	+0.404	+0.125	<.001	<.001	3	5
OV	AKAP12_T1760 →	+1.008	+0.112	.006	.002	3	4
BRCA	HK2 →	-0.617	-0.375	<.001	<.001	3	4
GBM	HSPA12A →	+0.720	+0.215	<.001	<.001	3	4
BRCA	HSPB6_S16 →	+0.994	+0.379	<.001	<.001	3	4
BRCA	ANK2 →	+0.441	+0.304	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,348 associations by consensus.

Exploration

KRT222 survival (RNA) · tumor vs normal (RNA) · all KRT222 data types