Across TCGA cell cohorts, KRT222 RNA expression is significantly associated with the go_rna of many other GO terms, with 381 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KRT222-associated GO terms across cancer lineages are Actin filament fragmentation, Regulation of attachment of mitotic spindle microtubules to kinetochore, and Regulation of cell cycle G1/S phase transition. Each is linked with KRT222 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT222-to-partner and partner-to-KRT222 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT222→partner) and Y-score (partner→KRT222) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Actin filament fragmentation →	+0.079	+0.013	.001	.002	3	4
BLOOD_Lymphoma	Regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.074	+0.017	.009	.004	3	3
BLOOD_Lymphoma	Regulation of cell cycle G1/S phase transition →	+0.037	+0.015	.002	.005	3	3
BLOOD_Lymphoma	Negative regulation of gene expression, epigenetic →	+0.040	+0.016	.004	.007	3	3
BLOOD_Lymphoma	Positive regulation of wound healing →	-0.063	-0.011	.002	.007	3	3
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein localization to synapse →	-0.095	-0.130	.004	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 381 associations by consensus.

Exploration

KRT222 survival (RNA) · tumor vs normal (RNA) · all KRT222 data types