KRT20

Across TCGA patient cohorts, KRT20 protein abundance is significantly associated with the RNA expression of many other genes, with 6,443 significant associations in total. COAD shows the largest number of these associations.

The most reproducible KRT20-associated genes across cancer lineages are DTHD1, AKR1B10, and ATP11AUN. Each is linked with KRT20 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT20-to-partner and partner-to-KRT20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT20 versus DTHD1 in LSCC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT20→partner) and Y-score (partner→KRT20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DTHD1 →	-0.713	-1.142	.002	.002	3	3
BRCA	AKR1B10 →	+1.075	+1.106	<.001	<.001	3	3
HNSC	ATP11AUN →	+0.095	+3.085	.001	.001	3	2
HNSC	ABHD11-AS1 →	+1.849	+3.677	.006	.006	3	2
HNSC	MIR5692C2 →	+3.222	+2.334	<.001	.002	3	2
COAD	SLA2 →	-0.530	-0.602	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,443 associations by consensus.

KRT20 vs DTHD1 — LSCC

Explore this scatter interactively →