KRT20

Across TCGA patient cohorts, KRT20 mutation is significantly associated with the RNA expression of many other genes, with 785 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT20-associated genes across cancer lineages are LINC00686, LINC01066, and MIR4472-2. Each is linked with KRT20 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT20-to-partner and partner-to-KRT20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00686 grouped by KRT20-low versus KRT20-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT20→partner) and Y-score (partner→KRT20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	LINC00686 →	+0.232	+5.653	<.001	.003	3	2
COAD	LINC01066 →	+0.206	+6.409	.001	<.001	3	2
COAD	MIR4472-2 →	+1.079	+4.893	<.001	.005	3	2
SKCM	RNGTTP1 →	+0.047	+2.395	<.001	<.001	3	2
LUAD	RNA5SP481 →	+0.650	+4.798	<.001	.006	3	2
UCEC	TSPAN7 →	-1.143	-2.159	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 785 associations by consensus.

LINC00686 by KRT20 expression — READ

Explore this box plot interactively →