KRT18P8

Across TCGA patient cohorts, KRT18P8 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,110 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible KRT18P8-associated GO terms across cancer lineages are Telomerase holoenzyme complex assembly, Positive regulation of low-density lipoprotein receptor activity, and Multi-pass transmembrane protein insertion into ER membrane. Each is linked with KRT18P8 in more than 17 cancer types. Because this analysis shows association rather than direction, both KRT18P8-to-partner and partner-to-KRT18P8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomerase holoenzyme complex assembly grouped by KRT18P8-low versus KRT18P8-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT18P8→partner) and Y-score (partner→KRT18P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Telomerase holoenzyme complex assembly →	+0.036	+0.188	<.001	.002	3	16
UCS	Positive regulation of low-density lipoprotein receptor activity →	+0.083	+0.196	.002	.006	1	18
TGCT	Multi-pass transmembrane protein insertion into ER membrane →	+0.048	+0.500	<.001	<.001	3	16
ESCA	Regulation of proton transport →	+0.061	+0.450	<.001	<.001	3	15
STAD	[4Fe-4S] cluster assembly →	+0.045	+0.454	<.001	<.001	3	15
TGCT	Galactose catabolic process →	+0.071	+0.545	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,110 associations by consensus.

Telomerase holoenzyme complex assembly by KRT18P8 expression — THYM

Explore this box plot interactively →