KRT18P57

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KRT18P57 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated KRT18P57 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher KRT18P57 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT18P57 expression acts as an unfavorable survival marker, although some lineages such as TGCT and PAAD show a favorable association.

LIHC, LGG, and MESO are the cancer types where KRT18P57 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCDFSTertileAll0.4420.596.00125view →
LGGDFSTertileAll0.2530.447<.00122view →
MESODFSQuartileIII,IV0.1890.394.00519view →
LUSCDFSTertileIII,IV0.3460.906.00716view →
DLBCDFSMedianAll0.6690.938.00513view →
KICHOSTertileIII,IV0.1960.702.03112view →
UVMDFSTertileAll0.3140.593.03912view →
TGCTDFSTertileAll0.9000.716.00512view →
PAADDFSQuartileII,III,IV0.5770.318.01112view →
KIRPOSMedianAll0.9280.838.00910view →
ESCAOSMedianIII,IV0.5520.313.01110view →
STADDFSQuartileAll0.5960.818.0477view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration