KRT18P55

Across TCGA patient cohorts, KRT18P55 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT18P55-associated genes across cancer lineages are TRGJP2, TRGJP1, and MIR320C2. Each is linked with KRT18P55 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT18P55-to-partner and partner-to-KRT18P55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRGJP2 grouped by KRT18P55-low versus KRT18P55-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT18P55→partner) and Y-score (partner→KRT18P55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRGJP2 →	+1.220	+4.473	<.001	.005	3	1
UCEC	TRGJP1 →	+2.065	+4.969	<.001	.002	3	1
UCEC	MIR320C2 →	+0.866	+4.694	<.001	.007	3	1
UCEC	RNU6-316P →	+0.555	+5.123	<.001	.004	3	1
UCEC	RNU2-28P →	+0.602	+4.233	.002	.009	3	1
UCEC	LINC02144 →	+0.198	+4.852	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

TRGJP2 by KRT18P55 expression — UCEC

Explore this box plot interactively →