KRT18P31

Across TCGA pan-cancer cohorts, KRT18P31 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated KRT18P31 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher KRT18P31 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated KRT18P31 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, UCS, and OV are the cancer types where KRT18P31 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.440	0.272	<.001	78	view →
UCS	OS	Median	III,IV	0.733	0.407	.008	52	view →
OV	DFS	Median	IV	0.224	0.410	.013	38	view →
LIHC	OS	Median	II,III,IV	0.486	0.715	.009	25	view →
SKCM	OS	Tertile	III,IV	0.445	0.279	.006	24	view →
LGG	OS	Tertile	All	0.416	0.617	<.001	18	view →
ESCA	OS	Median	All	0.396	0.575	.024	12	view →
SARC	DFS	Median	All	0.455	0.711	<.001	10	view →
CHOL	OS	Tertile	II,III,IV	0.372	0.878	.020	8	view →
BRCA	OS	Median	III,IV	0.628	0.440	.010	5	view →
THYM	DFS	Median	III,IV	1.000	0.484	.011	5	view →
READ	OS	Median	IV	0.520	1.000	.011	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

KRT18P31–HNSC (DFS)

Open the HNSC breakdown →