Q-omics provides the consensus-scored KRT18P31 profile across patient tissues and cancer cell-line models. KRT18P31 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, KRT18P31 is differentially expressed in 11, with the highest sampling consensus in STAD. Additionally, KRT18P31 RNA expression shows 14,299 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight HNSC, STAD, and THYM as cancer lineages where KRT18P31 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KRT18P31 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KRT18P31 survival associations across molecular data types. KRT18P31 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KRT18P31 RNA expression–survival associations across cancer types. High KRT18P31 expression shows unfavorable associations in OV, LIHC and LGG, but favorable associations in HNSC, UCS and SKCM. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for KRT18P31 RNA expression.
This table summarizes KRT18P31 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in STAD for RNA.
This table ranks reproducible tumor–normal expression differences for KRT18P31. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KRT18P31 shows higher tumor expression in STAD, UCEC, HNSC, LUSC, COAD and BRCA. The STAD box plot shows higher KRT18P31 RNA expression in tumor versus normal tissue (log2 FC = +0.502, t-test p < 0.001).
This table shows molecular features associated with KRT18P31 in patient tissues and cancer cell lines. In patient samples, KRT18P31 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
