KRT18P28

Across TCGA patient cohorts, KRT18P28 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,089 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KRT18P28-associated GO terms across cancer lineages are ERBB3 signaling pathway, Positive regulation of blood-brain barrier permeability, and Pyrimidine ribonucleoside triphosphate biosynthetic process. Each is linked with KRT18P28 in more than 13 cancer types. Because this analysis shows association rather than direction, both KRT18P28-to-partner and partner-to-KRT18P28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERBB3 signaling pathway grouped by KRT18P28-low versus KRT18P28-high in PAAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT18P28→partner) and Y-score (partner→KRT18P28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	ERBB3 signaling pathway →	+0.118	+0.274	<.001	<.001	3	14
ESCA	Positive regulation of blood-brain barrier permeability →	+0.154	+0.368	<.001	<.001	3	13
STAD	Pyrimidine ribonucleoside triphosphate biosynthetic process →	+0.040	+0.258	<.001	<.001	3	12
STAD	Blastocyst development →	+0.042	+0.218	<.001	.001	2	13
BLCA	Glial cell-derived neurotrophic factor receptor signaling pathway →	+0.116	+0.286	<.001	<.001	3	12
ESCA	Fatty acid alpha-oxidation →	+0.071	+0.291	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,089 associations by consensus.

ERBB3 signaling pathway by KRT18P28 expression — PAAD

Explore this box plot interactively →