KRT18P28

Across TCGA pan-cancer cohorts, KRT18P28 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated KRT18P28 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher KRT18P28 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT18P28 expression acts as an unfavorable survival marker, although some lineages such as BRCA and KIRP show a favorable association.

DLBC, HNSC, and LUAD are the cancer types where KRT18P28 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	II,III,IV	0.399	0.841	.004	75	view →
HNSC	OS	Median	All	0.278	0.425	<.001	68	view →
LUAD	OS	Median	All	0.271	0.450	<.001	65	view →
PAAD	OS	Quartile	All	0.282	0.572	<.001	55	view →
BRCA	DFS	Median	III,IV	0.878	0.711	<.001	39	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	36	view →
KIRP	DFS	Median	IV	0.812	0.041	<.001	30	view →
OV	OS	Quartile	II,III,IV	0.620	0.744	.008	24	view →
SKCM	DFS	Tertile	II,III,IV	0.445	0.645	.009	21	view →
COAD	OS	Tertile	All	0.913	0.764	.016	15	view →
LGG	OS	Tertile	All	0.785	0.897	.035	15	view →
THCA	OS	Tertile	All	1.000	0.898	.006	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

KRT18P28–DLBC (DFS)

Open the DLBC breakdown →