KRT18

Across TCGA patient cohorts, KRT18 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,387 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KRT18-associated proteins across cancer lineages are KRT8, KRT18_S305, and KRT18_S42. Each is linked with KRT18 in more than 8 cancer types. Because this analysis shows association rather than direction, both KRT18-to-partner and partner-to-KRT18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT18 versus KRT8 in BRCA, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT18→partner) and Y-score (partner→KRT18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KRT8 →	+0.963	+1.352	<.001	<.001	3	9
HNSC	KRT18_S305 →	+0.924	+1.795	<.001	<.001	3	7
LSCC	KRT18_S42 →	+0.894	+1.053	<.001	<.001	3	7
BRCA	KRT18_S53 →	+1.326	+1.304	<.001	<.001	3	7
BRCA	KRT18_S60 →	+1.062	+1.450	<.001	<.001	3	7
HNSC	KRT8_S24 →	+0.846	+1.200	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,387 associations by consensus.

KRT18 vs KRT8 — BRCA

Explore this scatter interactively →