KRT18

Across TCGA cell cohorts, KRT18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,545 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KRT18-associated GO terms across cancer lineages are Myofibril assembly, Establishment of protein localization to membrane, and Intestinal hexose absorption. Each is linked with KRT18 in more than 10 cancer types. Because this analysis shows association rather than direction, both KRT18-to-partner and partner-to-KRT18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myofibril assembly grouped by KRT18-low versus KRT18-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT18→partner) and Y-score (partner→KRT18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Myofibril assembly →	+0.247	+2.233	<.001	<.001	3	11
OVARY	Establishment of protein localization to membrane →	+0.050	+3.156	.002	.002	3	11
STOMACH	Intestinal hexose absorption →	+0.294	+3.659	<.001	.004	3	10
OVARY	Negative regulation of response to endoplasmic reticulum stress →	+0.083	+3.069	<.001	.001	3	10
LARGE_INTESTINE	Maternal process involved in parturition →	+1.033	+1.556	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of sodium ion transport →	+0.195	+2.337	.005	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,545 associations by consensus.

Myofibril assembly by KRT18 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →