KRT15

Across TCGA cell cohorts, KRT15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,300 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT15-associated GO terms across cancer lineages are Fibroblast migration, Positive regulation of transmission of nerve impulse, and Rho protein signal transduction. Each is linked with KRT15 in more than 9 cancer types. Because this analysis shows association rather than direction, both KRT15-to-partner and partner-to-KRT15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblast migration grouped by KRT15-low versus KRT15-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT15→partner) and Y-score (partner→KRT15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Fibroblast migration →	+0.155	+0.818	<.001	.008	2	10
LUNG_NSCLC_LUSC	Positive regulation of transmission of nerve impulse →	+1.850	+2.238	<.001	<.001	3	9
LARGE_INTESTINE	Rho protein signal transduction →	+0.135	+1.692	<.001	<.001	3	9
OVARY	Hemidesmosome assembly →	+0.241	+1.548	<.001	.001	3	9
STOMACH	Negative regulation of protein-containing complex disassembly →	+0.080	+2.526	<.001	.002	3	9
BONE	Positive regulation of extracellular exosome assembly →	+0.242	+2.082	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,300 associations by consensus.

Fibroblast migration by KRT15 expression — SOFT_TISSUE

Explore this box plot interactively →