KRT15

Across TCGA pan-cancer cohorts, KRT15 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated KRT15 data layer compared with 8 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher KRT15 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT15 expression acts as an unfavorable survival marker, although some lineages such as LUAD and BRCA show a favorable association.

KIRC, UCEC, and KIRP are the cancer types where KRT15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.494	0.743	<.001	190	view →
UCEC	DFS	Tertile	All	0.470	0.740	.001	42	view →
KIRP	DFS	Quartile	All	0.481	0.931	.003	39	view →
LUAD	OS	Tertile	III,IV	0.628	0.319	.002	37	view →
BRCA	OS	Median	All	0.658	0.509	<.001	37	view →
PAAD	OS	Median	All	0.460	0.705	.001	36	view →
LIHC	OS	Quartile	All	0.382	0.603	.005	30	view →
OV	DFS	Quartile	II,III,IV	0.359	0.472	.015	26	view →
SKCM	OS	Quartile	All	0.677	0.846	<.001	25	view →
STAD	OS	Median	All	0.515	0.252	.005	16	view →
LGG	DFS	Median	All	0.752	0.887	.001	16	view →
ACC	DFS	Quartile	III,IV	0.657	0.223	.010	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

KRT15–KIRC (DFS)

Open the KIRC breakdown →