KRT15

Across TCGA cell cohorts, KRT15 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT15-associated genes across cancer lineages are UCP1, SLC35G3, and LRIT2. Each is linked with KRT15 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT15-to-partner and partner-to-KRT15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UCP1 grouped by KRT15-low versus KRT15-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT15→partner) and Y-score (partner→KRT15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	UCP1 →	+0.095	+3.999	<.001	.004	3	1
SOFT_TISSUE	SLC35G3 →	+0.009	+3.635	<.001	.007	3	1
SOFT_TISSUE	LRIT2 →	+0.019	+4.169	<.001	.002	3	1
LARGE_INTESTINE	TUBA3E →	+0.084	+3.591	.008	.002	3	1
LARGE_INTESTINE	ACOT12 →	+0.032	+3.479	<.001	<.001	3	1
LARGE_INTESTINE	ADI1 →	+0.592	+3.215	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

UCP1 by KRT15 expression — SOFT_TISSUE

Explore this box plot interactively →