KRT14

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRT14 mutation is significantly associated with the RNA expression of many other genes, with 2,698 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT14-associated genes across cancer lineages are RN7SKP214, TRAJ57, and RNA5SP411. Each is linked with KRT14 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT14-to-partner and partner-to-KRT14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT14→partner) and Y-score (partner→KRT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SKP214 →+0.185+1.697.001.00632
UCECTRAJ57 →+0.443+2.126<.001.00232
UCECRNA5SP411 →+0.901+1.756<.001.00532
BRCARPL22P6 →+0.117+4.721<.001.00732
SKCMC1QL1P1 →+0.082+4.970<.001.00532
LIHCAK4P6 →+0.106+5.268<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,698 associations by consensus.

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