Across TCGA cell cohorts, KRT14 mutation is significantly associated with the mutation status of many other genes, with 1,993 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRT14-associated genes across cancer lineages are CHD8, INTS5, and ANKRD27. Each is linked with KRT14 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT14-to-partner and partner-to-KRT14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT14→partner) and Y-score (partner→KRT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CHD8 →	+2.975	+3.794	.006	.006	1	4
UPPER_AERODIGESTIVE_TRACT	INTS5 →	+5.392	+5.392	.004	.004	1	4
OESOPHAGUS	ANKRD27 →	+4.000	+3.087	.008	.008	1	3
OESOPHAGUS	PZP →	+4.000	+3.087	.008	.008	1	3
OESOPHAGUS	CPLANE1 →	+2.830	+3.146	.006	.006	1	3
UPPER_AERODIGESTIVE_TRACT	OGA →	+5.392	+5.392	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,993 associations by consensus.

Exploration

KRT14 survival (RNA) · tumor vs normal (RNA) · all KRT14 data types