Across TCGA patient cohorts, KRT12 protein abundance is significantly associated with the RNA expression of many other genes, with 1,565 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT12-associated genes across cancer lineages are LPIN1, AFDN-DT, and ST6GAL1. Each is linked with KRT12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT12-to-partner and partner-to-KRT12 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT12→partner) and Y-score (partner→KRT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LPIN1 →	-0.823	-1.109	<.001	<.001	3	2
BRCA	AFDN-DT →	-0.557	-1.201	.002	.008	3	2
HNSC	ST6GAL1 →	-1.235	-1.660	<.001	.001	3	2
LUAD	TSNAX →	+0.501	+1.170	.006	.008	3	2
LUAD	NSL1 →	+0.488	+1.476	.003	.005	3	2
BRCA	MRPS14 →	+0.507	+1.412	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,565 associations by consensus.

Exploration

KRT12 survival (RNA) · tumor vs normal (RNA) · all KRT12 data types