KRR1

Across TCGA pan-cancer cohorts, KRR1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated KRR1 data layer compared with 18 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher KRR1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRR1 expression acts as an unfavorable survival marker.

OV, SKCM, and ESCA are the cancer types where KRR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.076	0.844	<.001	48	view →
SKCM	DFS	Median	II,III,IV	0.255	0.696	<.001	34	view →
ESCA	OS	Median	III,IV	0.130	0.574	.011	18	view →
LIHC	OS	Median	All	0.105	0.777	<.001	9	view →
BLCA	DFS	Median	IV	0.083	0.476	.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

KRR1–OV (OS)

Open the OV breakdown →