KRR1

Across TCGA pan-cancer cohorts, KRR1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated KRR1 data layer compared with 18 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher KRR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRR1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and COAD show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where KRR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.445	0.781	<.001	55	view →
LSCC	DFS	Tertile	II,III,IV	0.872	0.471	.001	39	view →
LUAD	OS	Median	II,III,IV	0.481	0.748	.015	7	view →
COAD	DFS	Median	III,IV	1.000	0.844	.044	6	view →
GBM	OS	Quartile	All	0.571	0.236	.023	3	view →
HNSC	DFS	Quartile	II,III,IV	1.000	0.882	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

KRR1–CCRCC (DFS)

Open the CCRCC breakdown →