KRBOX4

Across TCGA patient cohorts, KRBOX4 mutation is significantly associated with the RNA expression of many other genes, with 2,540 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRBOX4-associated genes across cancer lineages are RNU4ATAC6P, NFYBP1, and MIR6803. Each is linked with KRBOX4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRBOX4-to-partner and partner-to-KRBOX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4ATAC6P grouped by KRBOX4-low versus KRBOX4-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRBOX4→partner) and Y-score (partner→KRBOX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU4ATAC6P →	+0.223	+8.471	<.001	.005	3	2
UCEC	NFYBP1 →	+0.157	+1.728	.001	.003	3	2
UCEC	MIR6803 →	+0.109	+3.954	<.001	.006	3	2
UCEC	SEPTIN14P19 →	+0.016	+3.370	<.001	.002	3	2
LUSC	RNU6-1258P →	+0.257	+7.924	<.001	.008	3	2
UCEC	PTPRJ →	+0.525	+3.480	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,540 associations by consensus.

RNU4ATAC6P by KRBOX4 expression — BRCA

Explore this box plot interactively →