KRBOX1

Across TCGA pan-cancer cohorts, KRBOX1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated KRBOX1 data layer compared with 1 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher KRBOX1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated KRBOX1 expression acts as an unfavorable survival marker, although some lineages such as DLBC and MESO show a favorable association.

DLBC, UCEC, and MESO are the cancer types where KRBOX1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Median	All	0.842	0.309	<.001	54	view →
UCEC	DFS	Tertile	All	0.772	0.885	<.001	36	view →
MESO	DFS	Median	IV	0.475	0.176	.002	35	view →
BRCA	DFS	Median	IV	0.519	0.903	.012	31	view →
LUAD	DFS	Quartile	All	0.480	0.167	.010	27	view →
STAD	DFS	Median	II,III,IV	0.458	0.594	.010	19	view →
THCA	DFS	Tertile	All	0.849	0.981	.008	19	view →
LUSC	DFS	Tertile	II,III,IV	0.282	0.455	.004	17	view →
UCS	DFS	Tertile	IV	0.942	0.323	.024	12	view →
KICH	OS	Tertile	II,III,IV	1.000	0.521	.031	12	view →
UVM	DFS	Median	III,IV	0.883	0.379	.029	9	view →
HNSC	DFS	Median	IV	0.553	0.334	.024	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

KRBOX1–DLBC (DFS)

Open the DLBC breakdown →