Across TCGA patient cohorts, KPRP protein abundance is significantly associated with the RNA expression of many other genes, with 2,921 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KPRP-associated genes across cancer lineages are LCE6A, YPEL1, and GRK3. Each is linked with KPRP in more than 1 cancer types. Because this analysis shows association rather than direction, both KPRP-to-partner and partner-to-KPRP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KPRP→partner) and Y-score (partner→KPRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LCE6A →	+1.186	+1.026	<.001	<.001	3	2
HNSC	YPEL1 →	-0.553	-0.923	.001	.002	3	1
HNSC	GRK3 →	-0.752	-1.189	.001	.001	3	1
HNSC	CRYBB1 →	-0.344	-1.000	.003	<.001	3	1
HNSC	SOX10 →	-0.832	-0.991	.002	.002	3	1
HNSC	CCDC134 →	-0.554	-1.071	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,921 associations by consensus.

Exploration

KPRP survival (RNA) · tumor vs normal (RNA) · all KPRP data types