Across TCGA pan-cancer cohorts, KPRP RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of KPRP’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where KPRP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KPRP is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LUSC, KIRC, and PAAD are the cancer types where KPRP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KPRP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+1.285	<.001	5	view →
KIRC	All	All	−0.007	.001	4	view →
PAAD	Male	All	+0.075	.037	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: KPRP RNA expression & survival · all KPRP data types