Across TCGA cell cohorts, KPRP RNA expression is significantly associated with the go_rna of many other GO terms, with 446 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KPRP-associated GO terms across cancer lineages are Negative regulation of calcineurin-NFAT signaling cascade, Regulation of plasminogen activation, and Zymogen activation. Each is linked with KPRP in more than 3 cancer types. Because this analysis shows association rather than direction, both KPRP-to-partner and partner-to-KPRP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KPRP→partner) and Y-score (partner→KPRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of calcineurin-NFAT signaling cascade →	+0.112	+0.029	<.001	.005	2	4
BONE	Regulation of plasminogen activation →	+0.223	+0.010	.002	.007	3	3
BONE	Zymogen activation →	+0.229	+0.007	<.001	.006	3	3
BONE	Plasminogen activation →	+0.239	+0.007	.003	.006	3	3
BONE	TRAM-dependent toll-like receptor signaling pathway →	+0.964	+0.011	<.001	.001	3	3
BONE	TRAM-dependent toll-like receptor 4 signaling pathway →	+0.964	+0.011	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 446 associations by consensus.

Exploration

KPRP survival (RNA) · tumor vs normal (RNA) · all KPRP data types