Across TCGA cell cohorts, KPRP mutation is significantly associated with the RNA expression of many other genes, with 168 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KPRP-associated genes across cancer lineages are LYPD4, NEUROD4, and ANKRD30A. Each is linked with KPRP in more than 1 cancer types. Because this analysis shows association rather than direction, both KPRP-to-partner and partner-to-KPRP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KPRP→partner) and Y-score (partner→KPRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	LYPD4 →	+0.175	+3.058	.006	.004	3	2
OESOPHAGUS	NEUROD4 →	+0.049	+4.017	.002	.007	3	1
OESOPHAGUS	ANKRD30A →	+0.034	+4.017	<.001	.007	3	1
KIDNEY	OR13C4 →	+0.023	+5.000	<.001	.005	3	1
KIDNEY	OR4F6 →	+0.056	+5.000	<.001	.005	3	1
SKIN	SFTPA1 →	+0.131	+3.115	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 168 associations by consensus.

Exploration

KPRP survival (RNA) · tumor vs normal (RNA) · all KPRP data types