KPNA6

Across TCGA patient cohorts, KPNA6 protein abundance is significantly associated with the RNA expression of many other genes, with 7,987 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KPNA6-associated genes across cancer lineages are TMEM39B, PSMB2, and EIF3I. Each is linked with KPNA6 in more than 4 cancer types. Because this analysis shows association rather than direction, both KPNA6-to-partner and partner-to-KPNA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPNA6 versus TMEM39B in BRCA, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA6→partner) and Y-score (partner→KPNA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMEM39B →	+0.457	+0.201	<.001	<.001	3	5
LSCC	PSMB2 →	+0.492	+0.213	<.001	<.001	3	5
LUAD	EIF3I →	+0.422	+0.177	<.001	<.001	3	5
LUAD	CPNE5 →	-0.556	-0.119	.002	.006	3	5
LUAD	TXLNA →	+0.587	+0.273	<.001	<.001	3	5
LSCC	ADPRS →	+0.605	+0.262	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,987 associations by consensus.

KPNA6 vs TMEM39B — BRCA

Explore this scatter interactively →