KPNA6

Across TCGA cell cohorts, KPNA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,157 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KPNA6-associated GO terms across cancer lineages are RISC complex assembly, Positive regulation of viral process, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with KPNA6 in more than 15 cancer types. Because this analysis shows association rather than direction, both KPNA6-to-partner and partner-to-KPNA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RISC complex assembly grouped by KPNA6-low versus KPNA6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA6→partner) and Y-score (partner→KPNA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RISC complex assembly →	+0.148	+0.795	<.001	<.001	3	16
BONE	Positive regulation of viral process →	+0.083	+0.672	<.001	<.001	3	16
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.092	+0.793	.002	.001	3	15
BLOOD_Lymphoma	Nuclear transport →	+0.076	+0.958	<.001	<.001	3	15
BLOOD_Lymphoma	Nucleocytoplasmic transport →	+0.075	+0.949	<.001	<.001	3	15
OESOPHAGUS	Intracellular transport of virus →	+0.244	+0.693	.001	.006	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,157 associations by consensus.

RISC complex assembly by KPNA6 expression — BONE

Explore this box plot interactively →