KPNA1

Across TCGA patient cohorts, KPNA1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,931 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KPNA1-associated genes across cancer lineages are NAA50, UMPS, and CCDC58. Each is linked with KPNA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both KPNA1-to-partner and partner-to-KPNA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPNA1 versus NAA50 in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA1→partner) and Y-score (partner→KPNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NAA50 →	+0.620	+0.264	<.001	<.001	3	8
LSCC	UMPS →	+0.830	+0.352	<.001	<.001	3	7
LSCC	CCDC58 →	+1.015	+0.383	<.001	<.001	3	7
OV	COX17 →	+0.782	+0.328	<.001	<.001	3	6
LSCC	MRPL3 →	+0.810	+0.327	<.001	<.001	3	6
LSCC	HACD2 →	+0.507	+0.293	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,931 associations by consensus.

KPNA1 vs NAA50 — LSCC

Explore this scatter interactively →