KPNA1

Across TCGA cell cohorts, KPNA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,360 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KPNA1-associated GO terms across cancer lineages are Postsynapse to nucleus signaling pathway, Nucleic acid transport, and RNA transport. Each is linked with KPNA1 in more than 17 cancer types. Because this analysis shows association rather than direction, both KPNA1-to-partner and partner-to-KPNA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Postsynapse to nucleus signaling pathway grouped by KPNA1-low versus KPNA1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA1→partner) and Y-score (partner→KPNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Postsynapse to nucleus signaling pathway →	+0.167	+0.813	<.001	<.001	3	18
PANCREAS	Nucleic acid transport →	+0.106	+0.850	<.001	<.001	3	16
PANCREAS	RNA transport →	+0.106	+0.850	<.001	<.001	3	16
LARGE_INTESTINE	Retrograde transport, endosome to Golgi →	+0.073	+0.992	<.001	<.001	3	15
LARGE_INTESTINE	Negative regulation of mitotic cell cycle phase transition →	+0.054	+0.848	<.001	<.001	3	15
BONE	Regulation of hippo signaling →	+0.075	+0.889	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,360 associations by consensus.

Postsynapse to nucleus signaling pathway by KPNA1 expression — LIVER

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