Across TCGA patient cohorts, KNTC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,894 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KNTC1-associated proteins across cancer lineages are RRM2, SMC2, and SMC4. Each is linked with KNTC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both KNTC1-to-partner and partner-to-KNTC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KNTC1→partner) and Y-score (partner→KNTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2 →	+0.878	+0.820	<.001	<.001	3	10
GBM	SMC2 →	+0.729	+0.745	<.001	<.001	3	10
GBM	SMC4 →	+0.648	+0.752	<.001	<.001	3	10
UCEC	LIG1 →	+0.507	+0.808	<.001	<.001	3	10
GBM	MCM2 →	+0.792	+0.874	<.001	<.001	3	10
LUAD	MCM3 →	+0.835	+0.811	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,894 associations by consensus.

Exploration

KNTC1 survival (RNA) · tumor vs normal (RNA) · all KNTC1 data types