KNSTRN

Across TCGA patient cohorts, KNSTRN RNA expression is significantly associated with the protein abundance of many other proteins, with 23,501 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KNSTRN-associated proteins across cancer lineages are MKI67_S357, TK1, and TOP2A. Each is linked with KNSTRN in more than 9 cancer types. Because this analysis shows association rather than direction, both KNSTRN-to-partner and partner-to-KNSTRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KNSTRN versus MKI67_S357 in LUAD, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KNSTRN→partner) and Y-score (partner→KNSTRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MKI67_S357 →	+1.535	+0.820	<.001	<.001	3	10
LUAD	TK1 →	+0.715	+0.735	<.001	<.001	3	9
LUAD	TOP2A →	+0.986	+0.726	<.001	<.001	3	9
LUAD	TOP2A_S1106 →	+1.184	+0.707	<.001	<.001	3	9
LUAD	TOP2A_S1247 →	+1.327	+0.712	<.001	<.001	3	9
LUAD	TRIP13 →	+0.755	+0.660	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,501 associations by consensus.

KNSTRN vs MKI67_S357 — LUAD

Explore this scatter interactively →