KNOP1P5

Across TCGA patient cohorts, KNOP1P5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,707 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KNOP1P5-associated GO terms across cancer lineages are Telomerase RNA localization, U2-type prespliceosome assembly, and DNA strand elongation. Each is linked with KNOP1P5 in more than 14 cancer types. Because this analysis shows association rather than direction, both KNOP1P5-to-partner and partner-to-KNOP1P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomerase RNA localization grouped by KNOP1P5-low versus KNOP1P5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KNOP1P5→partner) and Y-score (partner→KNOP1P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomerase RNA localization →	+0.062	+0.214	<.001	<.001	3	15
STAD	U2-type prespliceosome assembly →	+0.074	+0.259	<.001	<.001	3	15
STAD	DNA strand elongation →	+0.064	+0.270	<.001	<.001	3	14
ESCA	Positive regulation of telomerase RNA localization to Cajal body →	+0.076	+0.206	<.001	<.001	2	15
ESCA	Positive regulation of DNA-templated transcription initiation →	+0.071	+0.268	<.001	.002	3	14
STAD	Regulation of double-strand break repair via nonhomologous end joining →	+0.052	+0.270	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,707 associations by consensus.

Telomerase RNA localization by KNOP1P5 expression — STAD

Explore this box plot interactively →