lysine rich nucleolar protein 1 pseudogene 1Genealiases: []
Q-omics provides the consensus-scored KNOP1P1 profile across patient tissues and cancer cell-line models. KNOP1P1 expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, KNOP1P1 is differentially expressed in 1, with the highest sampling consensus in READ. Additionally, KNOP1P1 RNA expression shows 6,152 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight MESO, READ, and STAD as cancer lineages where KNOP1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KNOP1P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KNOP1P1 survival associations across molecular data types. KNOP1P1 RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KNOP1P1 RNA expression–survival associations across cancer types. High KNOP1P1 expression shows unfavorable associations in MESO, COAD, DLBC, KIRC, LUSC and BLCA. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for KNOP1P1 RNA expression.
This table summarizes KNOP1P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in READ for RNA.
This table ranks reproducible tumor–normal expression differences for KNOP1P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KNOP1P1 shows lower tumor expression in READ. The READ box plot shows higher KNOP1P1 RNA expression in normal versus tumor tissue (log2 FC = −0.085, t-test p = .029).
This table shows molecular features associated with KNOP1P1 in patient tissues and cancer cell lines. In patient samples, KNOP1P1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
