KNOP1

Across TCGA patient cohorts, KNOP1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,262 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KNOP1-associated genes across cancer lineages are PPP3CC, SYNE1, and ABCA6. Each is linked with KNOP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both KNOP1-to-partner and partner-to-KNOP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KNOP1 versus PPP3CC in OV, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KNOP1→partner) and Y-score (partner→KNOP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP3CC →	-0.654	-0.316	<.001	.009	3	6
LSCC	SYNE1 →	-0.766	-0.470	<.001	<.001	3	6
UCEC	ABCA6 →	-1.036	-0.407	<.001	<.001	3	6
UCEC	JAM2 →	-1.078	-0.414	<.001	<.001	3	6
BRCA	MEF2C →	-0.785	-0.606	<.001	<.001	3	6
OV	SRPX →	-1.283	-0.515	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,262 associations by consensus.

KNOP1 vs PPP3CC — OV

Explore this scatter interactively →