KNL1

Across TCGA patient cohorts, KNL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,234 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KNL1-associated proteins across cancer lineages are RPL12_S38, RRM1, and RRM2. Each is linked with KNL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both KNL1-to-partner and partner-to-KNL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KNL1 versus RPL12_S38 in LUAD, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KNL1→partner) and Y-score (partner→KNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL12_S38 →	+1.288	+1.097	<.001	<.001	3	10
COAD	RRM1 →	+0.488	+0.843	<.001	<.001	3	10
LUAD	RRM2 →	+0.917	+1.122	<.001	<.001	3	10
UCEC	SMC2 →	+0.769	+1.207	<.001	<.001	3	10
UCEC	SMC4 →	+0.721	+1.211	<.001	<.001	3	10
OV	KPNA2 →	+0.833	+1.238	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,234 associations by consensus.

KNL1 vs RPL12_S38 — LUAD

Explore this scatter interactively →