KNG1

Across TCGA pan-cancer cohorts, KNG1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated KNG1 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher KNG1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KNG1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

LUAD, COAD, and CCRCC are the cancer types where KNG1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.327	0.803	<.001	52	view →
COAD	DFS	Median	II,III,IV	0.880	1.000	.020	36	view →
CCRCC	DFS	Median	All	0.884	0.619	.002	17	view →
GBM	DFS	Median	All	0.438	0.207	.011	10	view →
HNSC	OS	Median	All	0.956	1.000	.014	5	view →
OV	DFS	Median	All	1.000	0.872	.044	4	view →
UCEC	DFS	Tertile	III,IV	0.409	1.000	.027	4	view →
LSCC	DFS	Tertile	II,III,IV	0.838	1.000	.023	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

KNG1–LUAD (OS)

Open the LUAD breakdown →