KNCN

Across TCGA patient cohorts, KNCN RNA expression is significantly associated with the go_rna of many other GO terms, with 6,969 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KNCN-associated GO terms across cancer lineages are Epithelial cilium movement involved in determination of left/right asymmetry, Motile cilium assembly, and Microtubule-based transport. Each is linked with KNCN in more than 13 cancer types. Because this analysis shows association rather than direction, both KNCN-to-partner and partner-to-KNCN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cilium movement involved in determination of left/right asymmetry grouped by KNCN-low versus KNCN-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KNCN→partner) and Y-score (partner→KNCN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cilium movement involved in determination of left/right asymmetry →	+0.091	+0.597	<.001	<.001	3	14
UCEC	Motile cilium assembly →	+0.069	+0.646	<.001	<.001	3	13
UCEC	Microtubule-based transport →	+0.038	+0.516	<.001	<.001	3	12
STAD	Cytoskeleton-dependent intracellular transport →	+0.041	+0.048	<.001	<.001	3	12
STAD	Protein-containing complex localization →	+0.035	+0.039	<.001	<.001	3	12
UCEC	Microtubule bundle formation →	+0.083	+0.626	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,969 associations by consensus.

Epithelial cilium movement involved in determination of left/right asymmetry by KNCN expression — UCEC

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